Respiratory Trend Report

Week ending November 16th, 2025

HealthTrackRx
Trend Update

Nationwide, influenza activity is now at 2.7% positivity, with the highest positivity seen in Texas, Louisiana, Alabama, and Florida. Texas currently has the highest influenza activity this week, with a positivity rate of 8.2%. Washington State lead influenza positivity last week at 6.5%, but this has fallen to 2.7% for the week of November 10th.

Like the current influenza rates, the positivity rate for RSV continues to climb and is at 2.7% positivity across the country this week. Florida leads RSV positivity, hovering at 11.0% positivity, with other states such as Texas and Georgia showing increasing RSV cases as well.

Respiratory Trend Report

Week ending November 16th, 2025

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HealthTrackRx
Trend Update

Nationwide, influenza activity is now at 2.7% positivity, with the highest positivity seen in Texas, Louisiana, Alabama, and Florida. Texas currently has the highest influenza activity this week, with a positivity rate of 8.2%. Washington State lead influenza positivity last week at 6.5%, but this has fallen to 2.7% for the week of November 10th.

Like the current influenza rates, the positivity rate for RSV continues to climb and is at 2.7% positivity across the country this week. Florida leads RSV positivity, hovering at 11.0% positivity, with other states such as Texas and Georgia showing increasing RSV cases as well.

Infection Trends

  • Rhinovirus/Enterovirus positivity is maintaining, hovering around 30% for the last 4 weeks.

  • Parainfluenza virus rates remain steady, currently at 8.1% after reaching what may be the seasonal peak of 8.8% the week of 10/12/25.

  • RSV reached 2.7% nationally, with higher rates observed in the Southeast.

  • Covid-19 circulation overall remains low at 1.7% nationwide, down from its high at 10% positivity the week of 8/17/2025.

Infection Trends

  • Rhinovirus/Enterovirus positivity is maintaining, hovering around 30% for the last 4 weeks.

  • Parainfluenza virus rates remain steady, currently at 8.1% after reaching what may be the seasonal peak of 8.8% the week of 10/12/25.

  • RSV reached 2.7% nationally, with higher rates observed in the Southeast.

  • Covid-19 circulation overall remains low at 1.7% nationwide, down from its high at 10% positivity the week of 8/17/2025.

Seasonal Outlook

  • RSV continues to circulate 2–3 weeks behind where it is typically expected nationally for mid-November. While southern states are seeing cases in line with seasonal expectations, it remains unclear why this trend has not extended to northern states. Is circulation simply delayed, suggesting a likely rise in RSV activity in the coming weeks? Or will low RSV rates persist throughout the respiratory season following the introduction of the RSV vaccination from the previous year? Positivity rates following the increased social interaction over the Thanksgiving holiday will provide valuable insight.

  • In contrast, influenza virus circulation appears to be following the expected national pattern, beginning in the southern states and spreading northward. Current increases in positivity suggest we can anticipate a typical influenza season.

  • COVID-19 activity remains low and stable following its seasonal high of 10% positivity during the late summer months.

Seasonal Outlook

  • RSV continues to circulate 2–3 weeks behind where it is typically expected nationally for mid-November. While southern states are seeing cases in line with seasonal expectations, it remains unclear why this trend has not extended to northern states. Is circulation simply delayed, suggesting a likely rise in RSV activity in the coming weeks? Or will low RSV rates persist throughout the respiratory season following the introduction of the RSV vaccination from the previous year? Positivity rates following the increased social interaction over the Thanksgiving holiday will provide valuable insight.

  • In contrast, influenza virus circulation appears to be following the expected national pattern, beginning in the southern states and spreading northward. Current increases in positivity suggest we can anticipate a typical influenza season.

  • COVID-19 activity remains low and stable following its seasonal high of 10% positivity during the late summer months.

Trending Up

  • Respiratory syncytial virus (RSV)

  • Influenza A/B

Trending Down

  • Enterovirus D68

  • COVID-19 Coronavirus (SARS-CoV-2)

Remaining Level

  • Parainfluenza (Types 1-4)

  • Adenovirus

  • Human metapneumovirus

  • Rhinovirus/ Enterovirus

  • Coronavirus (229E, NL63, OC43, and HKU1)

Trending Up

  • Respiratory syncytial virus (RSV)

  • Influenza A/B

Trending Down

  • Enterovirus D68

  • COVID-19 Coronavirus (SARS-CoV-2)

Remaining Level

  • Parainfluenza (Types 1-4)

  • Adenovirus

  • Human metapneumovirus

  • Rhinovirus/ Enterovirus

  • Coronavirus (229E, NL63, OC43, and HKU1)

7 Day Influenza Virus A/B Map

This report reflects observed trends in HealthTrackRx testing positivity data, does not convey medical advice, and is provided for informational purposes only. Individuals experiencing respiratory symptoms should consult with their healthcare provider.

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HealthTrackRx Respiratory Resource Library

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